| Item Type | Name |
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Concept
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Acylation
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Concept
|
Alcohol Oxidoreductases
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Concept
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1-Propanol
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Concept
|
Alcohol Dehydrogenase
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Concept
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Catalysis
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Concept
|
Circular Dichroism
|
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Concept
|
Chemistry
|
|
Concept
|
Bacterial Proteins
|
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Concept
|
Biological Transport
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Concept
|
Biophysics
|
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Concept
|
Birefringence
|
|
Concept
|
Electricity
|
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Concept
|
Chemistry, Physical
|
|
Concept
|
Cold Temperature
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Concept
|
Guinea Pigs
|
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Concept
|
Chromatography, Ion Exchange
|
|
Concept
|
Haptoglobins
|
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Concept
|
Hemoglobins
|
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Concept
|
Crystallography
|
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Concept
|
Hydrogen
|
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Concept
|
Diffusion
|
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Concept
|
Hemoglobin, Sickle
|
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Concept
|
Chromatography, High Pressure Liquid
|
|
Concept
|
Enzyme Activation
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Concept
|
Freezing
|
|
Concept
|
Electron Spin Resonance Spectroscopy
|
|
Concept
|
Hydrogen-Ion Concentration
|
|
Concept
|
Hypoglycemic Agents
|
|
Concept
|
Pentanones
|
|
Concept
|
Heme
|
|
Concept
|
Hydrolysis
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|
Concept
|
Models, Theoretical
|
|
Concept
|
Neoplasm Transplantation
|
|
Concept
|
Protein Denaturation
|
|
Concept
|
Optical Rotation
|
|
Concept
|
Pyrophosphatases
|
|
Concept
|
Pancreatic Elastase
|
|
Concept
|
Mutation
|
|
Concept
|
Paracoccus denitrificans
|
|
Concept
|
Peptide Fragments
|
|
Concept
|
Oxidation-Reduction
|
|
Concept
|
Optical Rotatory Dispersion
|
|
Concept
|
Penicillanic Acid
|
|
Concept
|
Peptide Elongation Factor Tu
|
|
Concept
|
Microscopy, Electron
|
|
Concept
|
Mitochondria, Heart
|
|
Concept
|
Phenylalanine
|
|
Concept
|
Phosphorylation
|
|
Concept
|
NAD
|
|
Concept
|
Magnetic Resonance Spectroscopy
|
|
Concept
|
Female
|
|
Concept
|
Porphyrins
|
|
Concept
|
Plasmids
|
|
Concept
|
Protein Binding
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|
Concept
|
Protein Conformation
|
|
Concept
|
Pyridoxamine
|
|
Concept
|
Quinones
|
|
Concept
|
Pyrrolidines
|
|
Concept
|
X-Ray Diffraction
|
|
Concept
|
Species Specificity
|
|
Concept
|
Spectrum Analysis
|
|
Concept
|
Spectrophotometry, Atomic
|
|
Concept
|
Humans
|
|
Concept
|
Spectrophotometry
|
|
Concept
|
Spectrophotometry, Infrared
|
|
Concept
|
Ultraviolet Rays
|
|
Concept
|
Mathematics
|
|
Concept
|
Protein Renaturation
|
|
Concept
|
Magnetics
|
|
Concept
|
Molecular Conformation
|
|
Concept
|
Mutagenesis, Site-Directed
|
|
Concept
|
Protein Structure, Tertiary
|
|
Concept
|
Anisotropy
|
|
Concept
|
Crystallography, X-Ray
|
|
Concept
|
Pancreas
|
|
Concept
|
GTP Phosphohydrolases
|
|
Concept
|
Protein Structure, Secondary
|
|
Concept
|
Drug Resistance, Bacterial
|
|
Concept
|
Positron-Emission Tomography
|
|
Concept
|
Phantoms, Imaging
|
|
Concept
|
Poloxamer
|
|
Concept
|
Peroxidases
|
|
Concept
|
Polyethylene Glycols
|
|
Concept
|
Piperidines
|
|
Concept
|
Recombinant Proteins
|
|
Concept
|
Spectrometry, Fluorescence
|
|
Concept
|
Static Electricity
|
|
Concept
|
Spectrophotometry, Ultraviolet
|
|
Concept
|
Stereoisomerism
|
|
Concept
|
Hydrophobic and Hydrophilic Interactions
|
|
Concept
|
Chemical Phenomena
|
|
Concept
|
Protein Tyrosine Phosphatase, Non-Receptor Type 1
|
|
Concept
|
Aldehyde Dehydrogenase
|
|
Concept
|
Crystallization
|
|
Concept
|
Horses
|
|
Concept
|
Hydroxybutyrates
|
|
Concept
|
Magnetic Resonance Imaging
|
|
Concept
|
Penicillin G
|
|
Concept
|
Peptides
|
|
Concept
|
Protons
|
|
Concept
|
Pyridones
|
|
Concept
|
Pyrones
|
|
Concept
|
Surface Properties
|
|
Concept
|
Protein Isoforms
|
|
Concept
|
Biophysical Phenomena
|
|
Academic Article
|
The vanadyl ion: molecular structure of coordinating ligands by electron paramagnetic resonance and electron nuclear double resonance spectroscopy.
|
|
Academic Article
|
Kinetically specific spin-label substrates of liver alcohol dehydrogenase and of liver aldehyde dehydrogenase.
|
|
Academic Article
|
In vivo spin-label murine pharmacodynamics using low-frequency electron paramagnetic resonance imaging.
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|
Academic Article
|
Electron nuclear double resonance determined structures of enzyme reaction intermediates: structural evidence for substrate destabilization.
|
|
Academic Article
|
ENDOR structural characterization of a catalytically competent acylenzyme reaction intermediate of wild-type TEM-1 beta-lactamase confirms glutamate-166 as the base catalyst.
|
|
Academic Article
|
The second derivative electronic absorption spectrum of cytochrome c oxidase in the Soret region.
|
|
Academic Article
|
Overexpression and biosynthetic deuterium enrichment of TEM-1 beta-lactamase for structural characterization by magnetic resonance methods.
|
|
Academic Article
|
Structural origins of the insulin-mimetic activity of bis(acetylacetonato)oxovanadium(IV).
|
|
Academic Article
|
Protonation of the beta-lactam nitrogen is the trigger event in the catalytic action of class A beta-lactamases.
|
|
Academic Article
|
ENDOR studies of VO2+: probing protein-metal ion interactions in nephrocalcin.
|
|
Academic Article
|
Structure of spin-labeled methylmethanethiolsulfonate in solution and bound to TEM-1 beta-lactamase determined by electron nuclear double resonance spectroscopy.
|
|
Academic Article
|
Reactivity and cryoenzymology of enzymes in the crystalline state.
|
|
Academic Article
|
Catalytic role of the metal ion of carboxypeptidase A in ester hydrolysis.
|
|
Academic Article
|
1H, 13C and 15N backbone resonance assignments for TEM-1, a 28.9 kDa beta-lactamase from E. coli.
|
|
Academic Article
|
Chromophoric spin-labeled beta-lactam antibiotics for ENDOR structural characterization of reaction intermediates of class A and class C beta-lactamases.
|
|
Academic Article
|
A surfactant copolymer facilitates functional recovery of heat-denatured lysozyme.
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|
Academic Article
|
The pH variation of steady-state kinetic parameters of site-specific Co(2+)-reconstituted liver alcohol dehydrogenase. A mechanistic probe for the assignment of metal-linked ionizations.
|
|
Academic Article
|
Assignment of proton endor resonances of nitroxyl spin-labels in frozen solution.
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|
Academic Article
|
Multi-block poloxamer surfactants suppress aggregation of denatured proteins.
|
|
Academic Article
|
The vanadyl (VO2+) chelate bis(acetylacetonato)oxovanadium(IV) potentiates tyrosine phosphorylation of the insulin receptor.
|
|
Academic Article
|
Synthesis of chromophoric, spin label enzyme substrates useful for cryoenzymology.
|
|
Academic Article
|
New vanadium-based magnetic resonance imaging probes: clinical potential for early detection of cancer.
|
|
Academic Article
|
Circular dichroism and electron paramagnetic resonance of the haptoglobin-hemoglobin complex.
|
|
Academic Article
|
Correlation of polarized absorption spectroscopic and X-ray diffraction studies of crystalline cytosolic aspartate aminotransferase of pig hearts.
|
|
Academic Article
|
Hydrolysis of esters by carboxypeptidase A requires a penta-coordinate metal ion.
|
|
Academic Article
|
Structure and conformation of the nitroxyl spin-label ethyl 3-(2,2,5,5-tetramethylpyrrolinyl-1-oxyl)-propen-2-oate determined by electron nuclear double resonance: comparison with the structure of a spin-label substrate of carboxypeptidase A.
|
|
Academic Article
|
Dynamical structure of carboxypeptidase A.
|
|
Academic Article
|
Structure at the active site of an acylenzyme of alpha-chymotrypsin and implications for the catalytic mechanism. An electron nuclear double resonance study.
|
|
Academic Article
|
Catalytic conformation of carboxypeptidase A. Structure of a true enzyme reaction intermediate determined by electron nuclear double resonance.
|
|
Academic Article
|
Polarized single crystal absorption spectra of carboxy- and oxyhemoglobin.
|
|
Academic Article
|
Neutral metal-bound water is the base catalyst in liver alcohol dehydrogenase.
|
|
Academic Article
|
Structure and mechanism of carboxypeptidase A.
|
|
Academic Article
|
Structural basis and dynamics of the fiber-to-crystal transition of sickle cell hemoglobin.
|
|
Academic Article
|
Mechanism of action of carboxypeptidase A in ester hydrolysis.
|
|
Academic Article
|
Catalytic conformation of carboxypeptidase A. The structure of a true reaction intermediate stabilized at subzero temperatures.
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|
Academic Article
|
Crystallographic and chemical studies on cytosolic aspartate aminotransferase.
|
|
Academic Article
|
Mg2+ is not catalytically required in the intrinsic and kirromycin-stimulated GTPase action of Thermus thermophilus EF-Tu.
|
|
Academic Article
|
Catalytic and structural role of the metal ion in dUTP pyrophosphatase.
|
|
Academic Article
|
Specificity of interaction of haptoglobin with mammalian hemoglobin.
|
|
Academic Article
|
Coordination environment of the active-site metal ion of liver alcohol dehydrogenase.
|
|
Academic Article
|
Optical spectra and electronic structure of flavine mononucleotide in flavodoxin crystals.
|
|
Academic Article
|
Fe-O2 bonding and oxyheme structure in myoglobin.
|
|
Academic Article
|
Structure of carboxymyoglobin in crystals and in solution.
|
|
Academic Article
|
Electron microscopy of fibers and discs of hemoglobin S having sixfold symmetry.
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|
Academic Article
|
Optically detected conformational changes in haemoglobin single crystals.
|
|
Academic Article
|
Electron microscope study of the kinetics of the fiber-to-crystal transition of sickle cell hemoglobin.
|
|
Academic Article
|
The vanadyl chelate bis(acetylacetonato)oxovanadium(IV) increases the fractional uptake of 2-(fluorine-18)-2-deoxy-D-glucose by cultured human breast carcinoma cells.
|
|
Academic Article
|
Kinetic characterization of the inhibition of protein tyrosine phosphatase-1B by Vanadyl (VO2+) chelates.
|
|
Academic Article
|
Preliminary investigation of 48V-labeled VO(acac)2 for cancer imaging: An initial proof-of-concept study.
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|
Concept
|
In Vitro Techniques
|
|
Academic Article
|
Efficient Synthesis and HPLC-Based Characterization for Developing Vanadium-48-Labeled Vanadyl Acetylacetonate as a Novel Cancer Radiotracer for PET Imaging.
|